To bring about sustainable stability in the MENA region depends on achieving acceptable solutions for Israeli-Palestinian conflict. All existing instabilities and conflicts in the MENA region are related to the un-acceptable relations between Israel and Palestine. Since WW-II the conflict between Israel and Palestine has been causing an endless chain of conflicts, instabilities, strains and wars on several scales with engagement of major powers around the world. Such instabilities have, also, major feedbacks and negative impacts on world economy. International security, and thereby world trade, will considerably benefit from finding lasting solutions for the Israeli-Palestinian conflict.