Among the most important indicators for life on earth are air and water qualities with poor qualities of air and water it becomes difficult, even impossible, to sustain life in any form. In some places in the world abuse of the natural resources, e.g. blind exploitation, production and use, have caused serious degradation and enormous damage, of natural environments. Exploitation, production and consumption are associated with environmental, ecological and human costs in form of “environmental, ecological and health degradation” and if such costs are not accounted for we will have negative sustainability balance. With gradual pile-up of such environmental, ecological and health debt, as is the case in the given examples, there would be no places on earth for suitable and sustainable life.          

http://www.mnn.com/earth-matters/wilderness-resources/photos/the-15-most-toxic-places-to-live/earths-orbit